Glucocorticosteroid ke ntho ea tlhaho ea tlhaho kapa ea tlhaho. E bua ka lihlopha tsa lihomone tsa adrenal cortex. Litokisetso tsa sehlopha sa glucocorticosteroids li na le phello ea immunosuppressive le ho eketsa sebopeho sa tsoekere sebeteng, kahoo li atisa ho sebelisoa ho phekola mafu a sa tšoaneng.
Glucocorticosteroids e ama 'mele joang?
Sepheo se seholo sa likokoana-hloko tsa glucocorticosteroids ke ho eketsa haholo ho hanyetsa khatello ea 'mele. Meriana ena e sebelisetsoa ho thibela khatello ea sesole ea 'mele, e lebisitsoeng ho setho sa motho. Boemo bona bo hlaha ha likokoana-hloko li e-na le likokoana-hloko, likokoana-hloko tse kotsi le maloetse a mangata. Ho phaella moo, glucocorticosteroids e ama mineral, metsi, lik'habohaedreite le protheine metabolism. Li boetse li sebelisoa e le li-anti-inflammatory, antitoxic le desensitizing agents. Phekolo e ka sebelisoa mefuta e joalo ea lithethefatsi:
- intranasal;
- karenteral;
- inhaled glucocorticosteroids.
Meriana ena e na le bokhoni ba ho phahamisa khatello ea mali. E phethahala ka lebaka la keketseho e kholo ea ho lokolloa ha adrenaline, hammoho le ho fokotseha ha lumen ea methapo ea mali. Sena se nolofalletsa ho sebelisa glucocorticosteroids ho sebetsana le maemo a tšosang maemong a maholo haholo.
Mabitso a lithethefatsi ho tswa ho sehlopha sa glucocorticosteroids
Ho na le litokisetso tse seng kae tsa sehlopha sa glucocorticosteroids, mme mabitso a ba bang ba bona ba tloaelane le batho ba bangata, hobane ba sebelisetsoa ho tšoara maloetse a tloaelehileng. Lisebelisoa tse ratoang ka ho fetisisa tsa mofuta ona:
- Belogen - tranelate kapa mafura bakeng sa tšebeliso e ka ntle. E sebelisetsoa ho phomola ha letsatsi , ho fapana le neurodermatitis, ho na le dermatitis e mengata.
- Sherisolone - matlapa a amanang le tsamaiso ea glucocorticosteroids. E ne e sebelisoa ho tšoara scleroderma , nodular periarteritis, ramatiki ea ramatiki.
- Cortonisol ke aerosol e sebelisetsoang ke colitis, lefu la Crohn's, proctitis le lefu la ulcerative colitis.
- Solu Medrol ke lyophilizate bakeng sa ho lokisetsa tharollo kapa ho emisoa ha metsi bakeng sa ente. E sebelisetsoa ho chesa le ho sebetsana le ts'oaetso, liphello tse bohloko tsa khatello ea mali.
Mong le e mong lithethefatsi ho tloha lethathamong la glucocorticosteroids o na le contraindications. Hoo e batlang e le efe kapa efe ea tsona ha ea lokela ho sebelisoa bakeng sa lefu la tsoekere, lefu la Cushing, thromboembolism le ho hlōleha ha renal haholo. Ha hoa hlokahala hore o phekoloe ka glucocorticosteroids nakong ea mofuta o sebetsang oa lefuba le syphilis.