Hypothalamus ke e 'ngoe ea litho tse ka sehloohong tsamaisong ea motho ea endocrine. E teng haufi le botlaaseng ba boko. Ke eena ea ikarabellang bakeng sa ts'ebetso e nepahetseng ea lesela la pituitary le metabolism e tloaelehileng. Li-Hormone tse hlahisoang hypothalamus ke tsa bohlokoa haholo bakeng sa 'mele. Ke li-peptide tse ikarabellang bakeng sa mekhoa e sa tšoaneng e hlahang 'meleng.
Ke li-hormone life tse hlahisoang ke hypothalamus?
Ho hypothalamus ho na le lisele tsa methapo, tse ikarabellang bakeng sa tlhahiso ea lihomone tsohle tsa bohlokoa. Li bitsoa li-neurosecretory cells. Ka motsotsoana, ba fumana maikutlo a fapaneng a methapo, a fanoang ke likarolo tse fapaneng tsa tsamaiso ea methapo. Li-axx tsa neurosecretory cells li felisoa ka methapo ea mali, moo li theha axo-vasal synapses. Ka li-hormone tsa ho qetela le tse hlahisoang li hlahisitsoe.
Hypothalamus e hlahisa li-liberin le li-statin - seo ho thoeng ke ho lokolla lihomone. Lintho tsena li hlokahala ho laola tšebetso ea lihomone tsa pituitary. Litokomane li na le boikarabelo ba ho fokotsa ho qaptjoa ha lintho tse ikemetseng, le liberia bakeng sa ho eketsa.
Ho fihlela joale, li-hormone tse ithutang hantle ka ho fetisisa tsa hypothalamus:
- Gonadoliberines. Li-hormona tsena li ikarabella ho eketsa palo ea lihomone tsa thobalano tse hlahisoang. Ba boetse ba kenya letsoho tšehetsong ea tloaelo ea ho ea khoeling le ho thehoa ha takatso ea thobalano. Tlas'a tšusumetso ea bongata ba lyuliberin - e 'ngoe ea mefuta e sa tšoaneng ea li-gonadotype - makhasi a hōlileng a mahe. Haeba li-hormone tsena li sa lekana, mosali a ka hlahisa ho hloka matla .
- Somatoliberin. Li-hormone tsena, tse hlahisitsoeng ke hypothalamus, lia hlokahala ho lokolla lintho tse kgolo. E tlameha ebe ba ntshetsopele ka ho fetisisa bongoaneng le bocha. Tabeng ea ho haelloa ke hormone, bothata bo bongata bo ka ba teng.
- Corticoliberin. E ikarabella bakeng sa tlhahiso e matla haholo ea lihomone tsa adrenocorticotropic phalong ea pituitary. Haeba hormone e sa hlahisoe ka tekanyo e hlokahalang, hangata ho haelloa ke adrenal ho hlaha.
- Prolactoliberin. Ntho ena e sebetsa ka matla haholo nakong ea bokhachane le nakong eohle ea lactation. Ntho ena e lokollang e eketsa boholo ba prolactine e hlahisitsoeng le e khothalletsang ntshetsopele ea likhahla ka har'a sefuba.
- Dopamine, melanostatin le somatostatin. Li thibela li-hormone tsa tropike tse hlahisoang ka letsoalo la pituitary.
- Melanoliberin. E kenya letsoho tlhahiso ea melanin le ho hlahisa li-pigment lisele tse ling.
- Tyroliberin. Ho bohlokoa ho arola lihomone tsa qoqotho le ho eketsa thyroxine maling.
Tlhophiso ea ho thibela li-hormone tsa hypothalamus
Tsamaiso ea methapo e arabela tsamaisong ea ho boloka li-hormone. Li-hormone tse eketsehileng li hlahisoa ke sekhahla sa tlhaho, e leng ho se sireletsehe ha li-hormone tsa tropike. Kamano ena e ke ke ea sebetsana le ho nyahamisa feela. Maemong a mang, e fetola phello ea lihomone tsa hypothalamus lisele tse karolong ea pituitary.
Meriana ea hormone bakeng sa hypothalamus
Tsena li kenyelletsa:
- Sermorelin. Setšoantšo sa tlhaho ea tlhaho ea hormone. E abeloa haholo-holo ho bana ba banyenyane haholo. E hanetsoe nakong ea bokhachane le nakong ea bokhachane.
- Bromocriptine. E ne e le ho susumetsa li-receptors tsa postsynaptic dopamine. E laeloa bakeng sa ho sitisoa ha lactation.
- Okreotid. E ka fokotsa tlhahiso ea li-hormone tse ntseng li hōla le ho thibela tšebetso ea likokoana-hloko tse nyenyane. E laeloa bakeng sa lisosa le likokoana-hloko tsa ho pata.
- Rifatiroin. An analogue ea hormone ea hypothalamus ea tiropropin.
- Stylamine. E ka fokotsa tšollo ea mali likarolong tsa ka hare, ntle le ho ama khatello ea mali ea systemic.