Litokisetso tse reretsoeng ho thibela ho itšireletsa mafung li bitsoa immunosuppressors, lebitso le leng le na le menyetla ea ho itšireletsa mafung. Sehlopha sena sa lithethefatsi, e le molao, se sebelisetsoa ho sebetsana le ho buoa ha setho sa 'mele.
Lithethefatsi tsa immunosuppressive - classification
Meriana e hlahlojoang e arotsoe ka lihlopha tse fapaneng ho ea ka phello ea tsona ho itšireletsa mafung:
- ho qobella ka ho feletseng lithethefatsi tsa meriana. Lisebelisoa tse joalo li ama likokoana-hloko tsohle tsa lisele tsa 'mele tsa ho itšireletsa mafung, li thibela mosebetsi oa tsona;
- khetha li-immunosuppressants bakeng sa merero e itseng ea mefuta e itseng ea lisele tsa 'mele tsa' mele. Ba sebetsa ka mokhoa o khethollang, ka mohlala, mekhoa ea ho itšireletsa mafung;
- meriana e nang le phello e khahlanong le ho ruruha, e sebelisoang maemong a mathata a bokooa;
- meriana ea matšoao. Karolo ena ea sehlooho e reretsoe feela ho fokotsa matšoao a mafu a mabeli.
Li-immunosuppressants
Li-immunosuppressors ke tsa bohlokoa haholo ho phekola maloetse a mabeli le lihlahala tsa kankere, kaha li na le phello e boima 'meleng. Ho feta moo, litlhare tsa tlhaho ha li na litla-morao, phekolo ha e ame sebete 'me ha e sitise mocheso.
Lipelong tsa li-immunosuppressants tsa tlhaho ea tlhaho ke metabolites ea bobeli (likokoana-hloko tse hlahang likokoana-hloko), li-microorganisms tse tlase le tse phahameng, liuk'uk'haaroute. Hangata mofuta oa Streptomyces o sebelisoa, hobane ke baemeli ba oona ba nang le lithibela-mafu tse sa khahlanong le ho ruruha, empa hape le liphello tsa antifuginal.
Lithethefatsi tsa immunosuppressive
Har'a li-immunosuppressor tse thibelang lisele leha e le life tsa ' mele tsa ho itšireletsa mafung le ho thibela sebopeho sa lymphocyte maling, se sebelisoang ka ho fetisisa ke:
- Vero-Cyclosporin;
- Li-cyclone;
- Imuran;
- Azathioprine.
Ka tloaelo, li-immunosuppressants tse thathamisitsoeng li sebelisitsoe phekolo ea li-tumor tsa kankere qetellong ea mekhahlelo le ka mor'a ho buuoa ha litho tsa 'mele, haholo-holo haeba ho haneloa ha mahlaseli a mangata ho qalile.
Litokisetso ka ketso e khethiloeng (e khethiloeng):
- Timodepressin;
- Tacrolimus;
- Cyclosporin A.
Li-immunosuppressors tsena li batla li sa thibele ho itšireletsa mafung, e se ke ea kena-kenana le sebopeho sa lisele tse sireletsang mafu a likokoana-hloko kapa a tšoaetsanoang.
Phoso ea ho thibela ho ruruha le ho felisoa ha matšoao a hlaselang , matšoao a mathata a likoloi a fanoa ke meriana e joalo:
- Methylprednisolone;
- Fluuocinonide;
- Clobetasol;
- Prednisolone;
- Hydrocortisone.
Re lokela ho hlokomela hore litokisetso tsa glucocorticosteroid li-immunosuppressants li na le litla-morao tse tebileng, tseo hangata li mpefatsang boemo ba mokuli feela. Sena se bakoa ke steroid ea tsona: meriana ena e kena-kenana le sebopeho sa lihomone tse hlokahalang tsa sebete le liphio.