Antidiuretic hormone kapa hormone vasopressin ke peptide. E na le litlhaka tse robong tsa amino acid. Bophelo ba eona halofo ke metsotso e 2-4. Hormone ena e hlahisoa likarolong tse khōlō tsa sele ea hypothalamus, 'me ho tloha moo e fetisetsoa ho "neurohyphysics". Ho tsamaisoa ho etsoa ka li-axon ka lebaka la liprotheine-veceme tse itseng.
Mesebetsi ea hormone vasopressin
Ketsahalo ea bohlokoa ea hormone ke taolo ea metsi metabolism. Ka hona, e bitsoa antidiuretic. Hang ha palo ea ADH e eketseha 'meleng, molumo oa moroto o lokolitsoeng ka matla o fokotseha.
Empa ha e le hantle ho bonahala hore vasopressin ke li-hormone tse ngata-ngata 'me li sebetsa' meleng li etsa chelete e tsotehang. Har'a tse bohlokoa ka ho fetisisa ho tsona ke:
- ho eketseha ha molumo oa mali o potolohang ka likepe;
- molumo oa mesifa o eketsehileng o boreleli;
- mosebetsi o eketsehileng oa lisele tsa mali tsa liplatelete;
- ho lokisa mekhoa ea ho hopola;
- ho fokotsa palo ea sodium e maling;
- phepo ea oli e nang le mafura a mafura.
Melao ea vasopressin
Haeba palo ea vasopressin e tšoana le e tloaelehileng liphellong tsa liteko, ha ho na mabaka a ho tšoenyeha. Melao e tloaelehileng ea litšupiso e shebahala joaloka ena:
- le osmolality ea plasma 270-280 mosm / kg -
- 280-285 Mosm / kg -
- 285-290 mosm / kg - 1-5 pg / mol;
- 290-295 mosm / kg - 2-7 pg / mol;
- 295-300 Mosm / kg - 4-12 pg / mol.
Ho ea ka molao-motheo oa liketso, li-hormone vasopressin le oxytocin li ka nkoa li tšoana haholo. Phapang e khōlō ke hore e qetellang e na le lihlahisoa tse peli tsa amino acid ka tlase. Empa sena ha se thibele hormone hore e se ke ea bontša mesebetsi e mengata ho fapana le ts'ebetso ea ho boloka lebese, ka mohlala.
Phoso ea hormone vasopressin
Haeba motsoako oa 'meleng ha o lekaneng, lefu la tsoekere la insipidus le ka hlaha. Lefu lena le khetholloa ke khatello ea ts'ebetsong ea metsi a ts'oaroang ke li-tubules tsa renal. Ho fokotsa boemo ba ADH bo tsamaisoa ke tšebeliso ea ethanol le glucocorticoids.
Hyperfunction ea antidiuretic hormone vasopressin
ADH e ka hlahisoa ka matla ka:
- ho imeloa maikutlong le 'meleng;
- ho hlōleha ha renal;
- ho se sebetse hantle ;
- ho fokotseha ha mali a potoloha betheng;
- li-porphyria tse mahlahahlaha;
- lihlahala tsa boko;
- pneumonia;
- meningitis e nang le lefuba.
Bothata ke ho fokotsa boleng ba plasma ea mali le ho lokolloa ha motsoako oa mahloriso a phahameng haholo.