Lefu la Werlhof - thrombocytopenic purpura - lefu le hlahisitsoeng ka mokhoa o fokolang oa metsi a mabeli ho latela mokokotlong oa aggregation (gluing) ea liplatelete. Metsoana e entsoeng ka likokoana-hloko e koala lisebelisoa tsa methapo e nyane. Ho phaella moo, ho na le ho qhibiliha ha lisele tsa mali le ho fokotseha ha palo ea liplatelete.
Lisosa tsa mafu a Werlhof
Hona joale, sesosa sa sebele sa thrombocytopenic purpura ha se tsejoe. Beha mefuta e meholo le ea bobeli ea lefu la Verlhof. Mefuta e ka sehloohong e na le tlhaho ea tlhaho kapa e bonahatsa ka lebaka la lefu le tšoaetsanoang. Mefuta e meng e tloaelehileng e na le matšoao a mafu a 'maloa.
Matšoao a Mafu a Verlhof
Lefu lena le qala ka matla, ka lebaka le utloahalang, ka nako e 'ngoe le khahlanong le semelo sa matšoao a mala kapa a ARI. Ha mokuli a le boemong ba pele, matšoao a latelang a bona a bonahala:
- feberu;
- ho nyefoloa (ho hlatsa ho ka etsahala);
- hlooho;
- bofokoli bo akaretsang, mokhathala;
- bohloko bofubeng le mpa.
Letšoao le ka sehloohong ke matetetso le li-hemorrhages, tse hlalosang lebitso la bobeli la lefu lena - thrombocytopenic purpura.
Kamora nako e khutšoanyane, lefu la hemorrhagic le iponahatsa haholo-holo ka mokhoa oa:
- ho tsoa mali, ho tsoa mali, 'me ho basali le bona uterine;
- mali a tsoa mali , liphatsa tsa lefutso;
- ho hemorrhages ho retina ea leihlo;
- hemoptysis.
Lipontšo tsa haemorrhagic li tsamaisana le mathata a kelello, a kang:
- ho lieha;
- ho otsela;
- ho senyeha ha nako le nako;
- ho fokotsa pono;
- ho se kopane le ho shoela litho.
Maemong a boima, ho ka khoneha ho hlahisa li-coma.
Hemorrhages tlase letlalong e ba ngata ebile e na le sebaka se seholo. Ho itšetlehile ka lengolo la ngaka, litsebe li na le 'mala o tsoang bofubelu bo bofubelu ho o mosehla (joaloka ho longoa khale).
Ho lemoha ha lefu la Verlhof ho qala ka tlhahlobo ea mokuli le anamnesis. Theknoloji ea ho hlahloba e akarelletsa liteko tse latelang:
- Tlhahlobo e tloaelehileng ea mali (OAK). Lefu lena le ikemiselitse ho fokotsa litekanyo tsa erythrocyte le hemoglobin, ho fokotsa palo ea li-platelets le ho bona li-antiplatelet antibodies.
- Sternary ho chesa - ho nka moko oa masapo bakeng sa tlhahlobo ka sternum puncture. Ha ho ntse ho hlahlojoa lisele tse ngata, ho eketseha ha palo ea megakaryocyte, palo e fokolang ea li-platelet, ho fumanoa, ha ho na liphetoho tse ling lerung la bone, ka mohlala, tse nang le litšobotsi tsa lihlahala.
- Trepanobiopsy - thuto ea bone ea masapo e nang le periosteum le bone (e tsoang sebakeng sa maqhubu), e nkiloe ka thuso ea sesebelisoa sa bongaka sa trephine. Ka lefu la Verlhof, karolelano ea mafura le hematopoietic bone ea marore e lumellana le se tloaelehileng.
Phekolo ea Mafu a Verlhof
Meriana ea phekolo e itšetlehile ka tsela ea lefu lena. Kalafo e etsoa ka e 'ngoe ea mekhoa e latelang:
- Tšebeliso ea corticosteroids ka morero oa ho tšoara lefu la hemorrhagic le ho eketsa boemo ba liplatelete maling. Prednisalon e laeloa ka tekanyo ea 1 mg ka ho 1 kg ea boima ba mokuli ka letsatsi. Haeba boemo bo tebileng ba lefu lena, tekanyo ea meriana e imenne habeli.
- Haeba phello e nepahetseng e sa finyelloe, mokuli o khothalletsoa ho tlosa spleen . Ho ea ka lipalo-palo tsa bongaka, bakuli ba 80% ka mor'a hore ba hlaphoheloe ka ho feletseng ba fumane phekolo e feletseng.
- Maemong a sa tloaelehang, ka mor'a spleenectomy ea spleen, li-passes tse tsoang mali, 'me lefu lena le ntse le tsoela pele, li-immunosuppressants li laeloa (Azathioprine, Vincristine) le glucocosteroids.
Ho tlosa matšoao a ka ntle a lefu la hemorrhagic, metsoako ea haemostatic e sebelisoa:
- Adroxone;
- Lijo;
- Seponche sa Hemostatic;
- estrogens.