Mokhoa o mong feela o sebetsang ho sebelisoa ha lithibela-mafu o tsoang libaktheria tsa likokoana-hloko ho fihlela joale ke phages kapa bacteriophages. Ke likokoana-hloko tse tobileng tse amang mefuta e sa tšoaneng ea likokoana-hloko. Lihlopha tse 'maloa li tsebahala ka meriana, tseo bacteriophages li arohanngoa ho tsona - mofuta le morero oa likokoana-hloko tsena li theha motheo oa kakaretso e amoheloang ka kakaretso.
Bacteriophages ke eng?
Ho na le malapa a 19 a li-virus tse potsoeng. Li fapane le mofuta oa nucleic acid (RNA kapa DNA), sebopeho sa genome le foromo.
Nakong ea bongaka, bacteriophages li aroloa ho ea ka tekanyo ea timetso ea libaktheria tse entsoeng ke likokoana-hloko:
- Bobebe. Lefu lena, ho kena liseleng tsa likokoana-hloko, le qala ho atoloha ka potlako le ka potlako, hang-hang le lebisa lefung la libaktheria (phello ea lytic).
- E ikhethang. Bacteriophages butle-butle 'me e senya karoloana ea likokoana-hloko tse phelang likokoana-hloko, empa e baka liphetoho tse sa fetoheng, tse fetisetsoang melokong e latelang ea likokoana-hloko (phello ea lysogenic).
Kajeno, likokoana-hloko tse hlalositsoeng li sebelisoa e le mokhoa o mong oa lithibela-mafu bakeng sa phekolo ea mafu a sa tšoaneng a baktheria. Har'a melemo ea bona, ke habohlokoa ho hlokomela melemo e latelang:
- Mokhoa o loketseng oa ho lokolloa. Bacteriophages li hlahisoa matlapeng le mokhoa oa tharollo bakeng sa tsamaiso ea molomo.
- Litla-morao tse fokolang. Ho fapana le lithibela-mafu, bacteriophages hangata e etsa hore liphatlalatso tsa mafu li se ke tsa hlahisa litholoana tse ling tse mpe bophelong.
- Ho hloka matla a likokoana-hloko. Libaktheria li thata haholo ho ikamahanya le likokoana-hloko, 'me liphello tse rarahaneng li batla li le thata.
Ho na le likotsi tse ling:
- nako e telele ea phekolo (ho fihlela ho matsatsi a 20);
- mathata le khetho ea sehlopha se nepahetseng sa lithethefatsi;
- ho fetisetsa likokoana-hloko tsa baktheria ho tloha likokoanyana tse ling ho ea ho tse ling.
Mefuta ea bacteriophages le tšebeliso ea tsona
Ho fanoa ka ho toba ka likokoana-hloko tse hlalositsoeng, meriana, libaktheria tse ngata tse rarahaneng le tse rarahaneng tse nang le mefuta e sa tšoaneng ea likokoana-hloko tsena li khethiloe.
Mona, bacteriophages ke eng - lenane le tlhaloso:
- Ka mpeng. Ho ameha hampe likokoana-hloko tsa feberu ea feberu, salmonella.
- Dysfag, lefu la mali le lekaneng. E sebelisetsoa ho ba le kankere ea baktheria, e baka lefu la Shigella Sonne le Flexner.
- Klebsifag, Klebsiella pneumonia. E thusa ho phekola maloetse a urogenital, ho senya lijo, mokhoa oa ho hema, mafu a mangata a sepakapaka , mafu a ho buoa a bakoang ke pneumonia klebsiella .
- Klebsiellezny ka tsela e tloaelehileng. Ke pheko e rarahaneng e senyang Klebsiella eseng feela pneumonia, empa le rhinoscleromas, ozena.
- Colitis, haeba. Ho atleha phekolo ea mafu a mang kapa afe a litho tsa ka hare le letlalo a bakoang ke E. coli entopathogenic E. coli.
- Coliproteophage, coliprotein. E mpe e ama lik'hemik'hale tse entsoeng ka hare ho metsoako ea Proteus le Escherichia. E reretsoe ho phekola lefu la colpitis, cystitis, colitis, pyelonephritis le maloetse a mang a bakoang ke mala a mala le a prost.
- Proteophagus, Protean. E bakoa ke lefu la proteus microbes mirabilis le vulgaris, tseo e leng mahlaseli a causative a mafu a purulent inflammatory pathologies a mala.
- Pseudomonas aeruginosa. Lysers baktheria pseudomonas aeruginosis. Ho kgothaletswa bakeng sa dysbiosis, hammoho le ho phekoloa ha ho ruruha mefuteng e sa tšoaneng ea 'mele e susumetsoang ke Pseudomonas aeruginosa.
- Staphylophage, staphylococcus. E se ke ea rarolla staphylococci ka potlako, e lokolloa ka lebaka la ho tšoaetsoa ke mafu leha e le ofe.
- Streptophagus, streptococcal. E tšoanang le mokhoa oa khato ho bacteriophage e fetileng, empa e sebetsa ka khahlanong le streptococci.
- Intersti. Ke mokhoa o rarahaneng oa ho lokisetsa lysing salmonella, shigella, E. coli , staphylococcus, enterococci, pseudomonas aeruginosa le proteus.
- Piopolyphage, e kopantsoeng piobacteriophage. Pheko e tšoana le mefuta e fetileng, empa e boetse e sebetsa ho tloha streptococci.
- Sextapage, pyobacteriophagous polyvalent. Ho feta moo o bolaea escherichia coli.
- Piobacteriophage e thata. Motsoako oa phagolysate ea entococci, streptococci, staphylococci, vulgaris le mirabilis proteasis, klebsiella oxytoca le pneumonia, escherichia coli, pseudomonas aeruginosis.