Alkaline phosphatase ke protheine e fanang ka tsela e tloaelehileng ea lik'hemik'hale tse ngata 'meleng. Ho kheloha ha setšoantšo ho tloha ho tloaelehileng ho atisa ho bontša tsoelo-pele ea mafu a itseng a amanang le ho tlōla phosphorus-calcium metabolism.
Norm ea alkaline phosphatase maling
Ho fumana hore na alkaline phosphatase e nepahetse kapa e kheloha ho tloaelehileng, tlhahlobo ea mali ea mali ea mali e etsoa. Re lokela ho hlokomela hore tloaelo ea alkaline phosphatase e amahanngoa le lilemo, thobalano, 'me maemong a mang boemo ba' mele ba mokuli. Ka hona, ho bana palo ena e feta makhetlo a mararo ho feta batho ba baholo, 'me ho basali, boemo ba alkaline phosphatase maling bo fokotsehile ho feta banna.
Ho phaella moo, hoa lokela ho hlokomeloa hore litekanyo tsa alkaline phosphatase tekanyo e itšetlehile ka li-reagents tse sebelisoang tlhahlobo ea mali. Re fana ka likhetho tse fapaneng.
Melao ea mali ea APF tlhahlobo ea likokoana-hloko (mokhoa o tsitsitseng oa nako):
- bana le bacha - 1,2-6,3 mcd / l;
- ho banna - 0,9-2,3 mkat / l;
- tloaelo ea alkaline phosphatase ho basali ke 0,7-2,1 mc / l.
Tloaelo ea tlhokomelo ho bana ba li-enzyme tse fanoeng ka mali a mali:
- ho tloha ho tsoalo ho fihlela ho 1 selemo - li-unit tse 245-255 / l;
- ho tloha ho 1 selemo ho ea ho tse 9 - li-units tsa 345-355 / l;
- ho tloha lilemong tsa 9 ho isa ho tse 15 - diyuniti tse 275-285 / l;
- ho tloha ho lilemo tse 15 ho isa ho tse 18 - ho isa ho 145-155 diyuniti / litare.
Keketseho e kholo ea AF ea bana ba ka tlase ho lilemo tse 9 hase bothata ba ho kula 'me e amahanngoa le kholo ea kholo ea bone.
Ho banna, litaba tsa li-enzyme tsa sehlopha sena ke tsa tlhaho:
- ho tloha lilemong tsa 18 ho isa ho tse 45 - diyuniti tse 100-120;
- ho tloha lilemong tse 45 ho isa ho tse 70 - diyuniti tse 120-145;
- ka mor'a lilemo tse 70 - diyuniti tse 180-190.
Mokhoa oa alkaline phosphatase ka mali a mali a basali (ka lilemo):
- ho tloha ho lilemo tse 19 ho isa ho tse 45 - diyuniti tse 80-100. / l;
- ho tloha lilemong tse 45 ho isa ho tse 55 - diyuniti tse 105-115 / l;
- ho tloha lilemong tsa 55 ho isa ho tse 70 - diyuniti tsa 125-135 / l;
- ka mor'a lilemo tse 70 - liraiti / litara tse 155-165.
Ho tloaelehile ho fetola tekanyo ea enzyme nakong ea bokhachane. Sena se bakoa ke ho thehoa ha placenta 'meleng oa' mè oa ka moso.
Litho tsa mafu li bakoa ke liphetoho tsa alkaline phosphatase
Hammoho le lipatlisiso tse ling tsa laboratori le lithuto tsa li-instrumental, ho fumanoa ha litekanyetso tsa alkaline phosphatase ke habohlokoa haholo ha ho fumanoa mafu a itseng. Ho hlahlojoa ha liphatsa tsa lefutso ho fuoe bakuli ba nang le lefu la ho qetela ha tsamaiso ea endocrine, pampiri ea lijo, sebete, liphio. Ha ho pelaelo hore thuto ena e etsoa le basali ba nang le bakhachane le bakuli ba itokiselitseng ho buuoa.
Ka lebaka la tšenyo ho lisele tsa setho kapa tsamaiso, boemo ba alkaline phosphatase bo fetoha. Kenya letsoho ho lefu lena:
- sebete (cirrhosis, kokoana-hloko ea kokoana-hloko ea kokoana-hloko, li-jaundice );
- bile ducts;
- linama tsa bone (rickets, sarcoma osteogenic, osteomalacia, joalo-joalo);
- lihlapa tse bohloko;
- ramatiki ea ramatiki;
- tšoaetso ea lik'hemik'hale;
- ho hloleha ha renal;
- Lefu la ho ruruha le lefu la entestinal le tsamaeang le letšollo;
- mathata a qoqotho.
Melao ea tlhahlobo ea likokoana-hloko
E le hore u fumane data e nepahetseng ka ho fetisisa, u tlameha ho latela melao e latelang:
- Letsatsi pele ho ts'ebetso eo ho thibetsoe ho kena mosebetsing o matla oa lipapali kapa lipapaling.
- Metsotso e ka tlase ho li 24 li buelloa hore u se ke ua noa joala 'me u se ke ua sebelisa meriana e tlatsetsang liphetohong tse ling tsa alkaline phosphatase.
- Tlhahlobo e etsoa ka mpeng e se nang letho hoseng.
- Sampuli ea mali e tsoang meleng ea tlhahlobo bakeng sa ho hlahlobisoa e etsoa ka boholo ba li-5-10 di ml.
Ho phaella moo, e le hore ho hlakisoe ho fumanoa, motsoako, litlolo tsa mokokotlo, lero la "intestinal" li ka abeloa, 'me li-hepatic, intestinal, bone, placental, isoenzymes tsa alkaline phosphatase li ka etsoa.