Sebaka ke metsi a botala bo botala a nang le sebete (hepatocytes) a tsoelang pele.
Bete e nang le metsoako e bokellana ka li-ducts, 'me ho tloha moo e kena gallbladder le duodenum, moo e nkang karolo e mafolofolo tshebetsong ea tshilo ea lijo. Hafeela bile e ntse e tsamaea ka maleng, bongata ba eona bo kenngoa ke limatlafatsi, 'me tse ling kaofela li tlosoa' meleng hammoho le lithla tse ling.
Haeba mesebetsi ea ho thehoa ha bile ka lebaka leha e le efe e tlōloa, joale lefu la sebete le lefuba la ho ruruha lea kula, ho feta moo, ts'oaetso e senyeha. Tabeng ena, rera litokisetso tsa choleretic, lethathamo le lenaneo leo ka mokhoa o fokolang, re tla leka ho hlahisa ka tlase.
Lithethefatsi tse hlaselang
Khetholla mekhoa ea ho khetholla seretse:
- tlhaho ea tlhaho (nkhono ea artichoke, tansy, metso ea burdock, likokoanyana tsa poone, metso ea dandelion, makhasi a nettle, immortelle, joalo-joalo);
- maiketsetso.
Ho ea ka mokhoa oa liketso (pharmacodynamics), lihlopha tsa mekhoa ea mehleng ea kajeno ea li-cholagogue li ngata haholo, empa kaofela ha tsona li ka kopantsoe ka lihlopha tse peli:
- Choleretics - matlafatsa sebopeho sa bile acid (LC) le bile.
- Cholekinetics le cholespismolytics - ntlafatsa excretion ea bile ka duodenum ka ho susumetsa thibelo ea gallbladder kapa ka tsela e fapaneng ho phomola sphincter ea Oddi le musculature ea bile ducts.
Tsamaiso ena e na le meeli, kaha bongata ba litokisetso tsa ts'ebetso ea ts'ebetso e ts'oanang e ntlafatsa ka bobeli tlhahiso ea pele le ho khutsuoa ha bile.
Choleretics
Sehlopha sena sa meriana e hlaselang, hape, se na le lihlopha tse latelang.
Li-choleretics tsa 'nete ke lithethefatsi, tse khethehileng tsa tsona ke ho eketsa sephiri sa bile le lactic acid. Meriana ena e ka:
- na le LCD ka ho toba (Holenzim, Allochol, Vigheratin, joalo-joalo);
- u etse lihlahisoa (Nikodin, Oxafenamid, Tsikvalon, Odeston, joalo-joalo);
- li tsoa tlhaho (Tanachevol, Holosas, Flakumin, Convaflavin, joalo-joalo);
Hydrocholeretics ke lithethefatsi tse eketsang tlhahiso ea bile ka lisele tsa sebete ka lebaka la karolo ea metsi. Har'a sehlopha sena, litokisetso tse ntle ka ho fetisisa tsa cholaogogue li emeloa ke metsi a nang le diminerale (Jermuk, Essentuki No. 17, No. 4, Izhevskaya, joalo-joalo), salicylate ea sodium le lihlahisoa tsa valerian.
Litokisetso tsa sehlopha sena li laeloa bakeng sa maloetse a sa foleng a sebete a sa foleng; ho tlōla ho tsoa ha bile (dyskinesia ea bile ducts). Haeba ho hlokahala, lithethefatsi tsena li kopantsoe le lithibela-mafu, li-laxative, analgesics.
Cholekinetics le choleospasmolytics
Ho lisebelisoa, phello ea eona e fanang ka keketseho ea molumo oa gallbladder le ducts (cholekinetics), kenyeletsa:
- sulfate ea magnesium;
- cholecystokinin;
- litokisetso tse thehiloeng ho barberry ;
- mannitol;
- choleritine;
- pituitrin;
- sorbitol;
- xylitol.
Litokisetso tsena tse khetholloang ka bongata li bontšoa bakeng sa cholecystitis e sa foleng, ho tlōla ho tsoa ha bile (dyskinesia), atony ea gallbladder, e sa foleng lefu la sebete.
Lintho tse phomollang mesifa ea bile (holespazmolitiki):
- platyphylline;
- atropine;
- iodide ea metocinium;
- ho tlosoa belladonna;
- aminophylline;
- papaverine;
- drotaverine;
- mebeverin;
- olimethine.
Sehlopha sena sa litokisetso tsa choleretic se sebetsa bakeng sa cholelithiasis le dyskinesia ea mofuta oa hyperkinetic.
Hlokomela
Hlalosa meriana e thathamisitsoeng e lokela ho ba ngaka feela, kaha liketso tsa bona li fapane. Ka mohlala, litokisetso tsa ho jala likokoana-hloko tsa giardiasis, 'me ka ho pholletsa le lefu, cholecystitis , lefu la sebete le tla fapana. Ka hona, ho ipeha meriana ho ka eketsa setšoantšo sa lefu lena feela.